Antimicrobial Resistance of Staphylococcus Aureus in Blood Cultures
Keywords:
Gram-positive bacteria, drug resistance bacteria, microbiology, Staphylococcus aureusAbstract
Introduction: Staphylococcus aureus is responsible for a large number of isolations in health services. In the province of Mayabeque, it is one of the main pathogens of interest due to its ability to resist antimicrobials, and proper monitoring of this is vital.
Objective: To characterize the antimicrobial resistance of Staphylococcus aureus isolated in blood cultures.
Methods: An observational, descriptive, cross-sectional study was carried out. The universe was made up of the 60 blood cultures that were processed during the year 2023. The six blood cultures positive for Staphylococcus aureus were selected as a sample. Statistical analysis was used. The variables were: number of processed blood cultures, service of origin and antimicrobial resistance, a variable evaluated according to the availability of antimicrobial discs in the hospital.
Results: Of the 60 processed blood cultures, six were positive for Staphylococcus aureus, 10%, the Service with the highest incidence was Internal Medicine (n=4, 66.67%). Erythromycin turned out to be the antimicrobial with the highest resistance, with (n=5, 83.33%), while the one with the best sensitivity was chloramphenicol (n=5, 83.33%).
Conclusions: The incidence of positive blood cultures for Staphylococcus aureus during 2023 was low. The Internal Medicine Service provides the highest number of positive samples. Erythromycin stands out for its low effectiveness, on the contrary, chloramphenicol shows high efficacy in treating infections associated with the germ.
Downloads
References
Giono Cerezo S, Santos Preciado JI, Morfín Otero MR, Torres López FJ, Alcántar Curiel MD. Resistencia antimicrobiana. Importancia y esfuerzos por contenerla. Gac. Méd. Méx [Internet]. 2020 [citado: 10/12/2023]; 156(2): 172-80. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0016-38132020000200172&lng=es
Oteo Iglesias J. Comprendiendo la resistencia a antibióticos. RIECS. 2019 [citado: 10/12/2023]; 4 (2): 84-9. DOI: https://doi.org/10.37536/RIECS.2019.4.2.164
World Health Organization. Antimicrobial resistance [Internet]. Geneva: WHO; 2023. [citado: 10/5/2024]. Disponible en: https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance
Guo Y, Song G, Sun M, Wang J, Wang Y. Prevalence and Therapies of Antibiotic-Resistence in Staphylococcus aereus. Front. Cell Infect. Microbiol. [Internet]. 2020 [citado: 10/5/2024]; 10: [aprox. 10p]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089872/pdf/fcimb-10-00107.pdf
García Fenoll R, Espinosa Pérez M, Mormeneo Bayo S, Frutos Millán V, Martínez Jiménez MC, Martínez Álvarez RM, et al. Características clínicas, pronóstico y factores asociados de la bacteriemia por Staphylococcus aureus en la actualidad. Rev Esp Quimioter [Internet]. 2022 [citado: 10/5/2024]; 35(6): 544-50. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9728609/pdf/revespquimioter-35-544.pdf
Linz MS, Mattappallil A, Finkel D, Parker D. Clinical Impact of Staphylococcus aureus Skin and Soft Tissue Infections. Antibiotics [Internet]. 2023 [citado: 15/5/2024]; 12(3): [aprox. 26p]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044708/pdf/antibiotics-12-00557.pdf
Abreu Pereira LM, Tarife Romero IE. Resistencia antimicrobiana del Staphylococcus aureus aislados en hemocultivos en el Laboratorio de Microbiología del Hospital Aleida Fernández Chardiet. EsTuSalud [Internet]. 2023 [citado: 15/5/2024]; 5(1): [aprox. 7 p]. Disponible en: https://revestusalud.sld.cu/index.php/estusalud/article/view/339
CLSI. Performance Standars for Antimicrobial Suceptibility Testing. 30 ed. CLSI supplement M100. Wayne, PA: Clinical and Laboratory Standars Institute; 2020. Disponible en: https://www.nih.org.pk/wp-content/uploads/2021/02/CLSI-2020.pdf
Milá Pascual MC, Campos Bestard I, Torres Milá I, Aties López L. Hemocultivos de pacientes ingresados en el Hospital Clínico Quirúrgico Dr. Ambrosio Grillo Portuondo, Santiago de Cuba. Rev. electron. Zoilo [Internet]. 2021 [citado: 15/5/2024]; 46(1): [aprox. 7 p]. Disponible en: https://revzoilomarinello.sld.cu/index.php/zmv/article/view/2480
Sanmartín Orbe ML, Andrande Tacuri CF, Orellana Bravo PP. Susceptibilidad de cepas de S. aureus aisladas en superficies hospitalarias. Vive [Internet]. 2021 [citado: 15/5/2024]; 4(11): 233-45. Disponible en: http://www.scielo.org.bo/pdf/vrs/v4n11/2664-3243-vrs-4-11-233.pdf
Castañeda Méndez PF, Hernández Juarez D, Muñoz López M, Soto Ramírez LE. Frecuencia de infecciones por S. aureus en pacientes hospitalizados en un hospital privado de tercer nivel de la Ciudad de México. Rev. Med. MD [Internet]. 2018 [citado: 15/5/2024]; 9(4): 317-21. Disponible en: https://www.medigraphic.com/pdfs/revmed/md-2018/md184i.pdf
Márquez Oviedo A, Romero Coasaca AC, Requena Mendizábal MF, Martínez Cadillo E, Mongrut Villegas U, Ayón Haro ER, et al. Resistencia de Cepas de Staphylococcus aureus aisladas de la Mucosa Oral de una Población Joven Peruana. Int. J. Odontostomat. [Internet]. 2021 [citado: 15/5/2024]; 15(3): 634-8. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2021000300634&lng=es
Cabrejos Hirashima L, Vives Kufoy C, Inga Salazar J, Astocondor L, Hinostroza N, García C. Frecuencia de Staphylococcus aureus meticilinorresistente adquirido en la comunidad en un hospital de tercer nivel en Perú. Rev. perú. Med. Exp. salud publica [Internet]. 2021 [citado: 15/5/2024]; 38(2): 313- 7. Disponible en: https://doi.org/10.178443/rpmesp.2021.382.6867.
Monzote López A, Toraño Peraza G, Diaz Novo L, Valdés Dapena-Vivanco M. Incremento de las infecciones por Staphylococcus aureus resistente a meticilina en un hospital pediátrico de Cuba. Panorama. Cuba y Salud [Internet]. 2016 [citado: 15/5/2024]; 11(1): 9-15. Disponible en: https://revpanorama.sld.cu/index.php/panorama/article/view/554
Salcedo Libreros LF, Ponce Ramírez MA, Ortegón Henao MP, Bravo Narvaez LY, Velásquez Palomino A, Torres Martínez CA, et al. Staphylococcus aureus and susceptibility in a hospital Level II in Palmira-Colombia. Rev Colomb Salud Libre. [Internet]. 2020; 15(2): 1-15. Disponible en: https://revistas.unilibre.edu.co/index.php/rcslibre/article/view/7188/6960
Duran Lengua M, Valladales Restrepo L, Caraballo Marimón R, Romero Martínez G, Cabarcas Tovar A, Bohórquez Moreno C. Prevalencia de resistencia de bacterias aisladas en hemocultivos, en un hospital universitario de Colombia. Nova [Internet]. 2021 [citado: 10/5/2024]; 19(37): 57-69. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S1794-24702021000200057&lng=en
Vargas Zabala DL, Cabrera Velasco C, Lozano Fernández V, Cardeño Sanchez J, Vargas Uricoechea H. Perfil microbiológico y de resistencia antimicrobiana en infecciones adquiridas en la comunidad. Hospital Universitario San José de Popayán. Infectio [Internet]. 2021 [citado: 10/5/2024]; 25(1): 39-44. Disponible en: https://prueba.revistainfectio.org/index.php/infectio/article/view/907/1005
Herrero Díaz A, Martínez Suárez CL, Abreu Pereira LM, Tarife Romero IE, López Berrio S, Espinosa Goire Y. Resistencia antimicrobiana de Staphylococcus aureus aislados en hemocultivos de un hospital de Villa Clara. Inmedsur [Internet]. 2024 [citado: 10/5/2024]; 7(1): 1-7. Disponible en: http://www.inmedsur.cfg.sld.cu/index.php/inmedsur/article/view/300
Castellano González MJ, Franquis Rodríguez RM, Perozo Mena AJ, Sandoval Castellano IV. Susceptibilidad a meticilina y vancomicina en Staphylococcus aureus aislados de hemocultivos. Kasmera [Internet]. 2020 [citado: 10/5/2024]; 48(1): [Aprox. 13p]. Disponible en: https://www.redalyc.org/journal/3730/373064123007/html/
Herrero Díaz A, López Berrio S, Rodríguez Villavicencio K, Paz Treto JL, Cárdenas López L. Resistencia antimicrobiana de Staphylococcus aureus aislado en cultivos del laboratorio de Microbiología, Hospital Mártires del 9 de abril. Colum méd. [Internet]. 2024 [citado: 15/5/2024]; 3: 8-13. Disponible en: https://www.revcolumnamedica.sld.cu/index.php/columnamedica/article/view/165
Hernández Sarmiento R, Bustamante Gómez L, Lesport Castro LP, Nassar Mendoza N, Méndez Rodríguez I. Prevalencia y perfil de susceptibilidad de Staphylococcus aureus meticilino resistente de fenotipo comunitario en jóvenes deportistas. Rev. mex. Pediatr. [Internet]. 2019 [citado: 15/5/2024]; 86(1): 13-7. Disponible en: https://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0035-00522019000100013
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Annelis Marrero Fernández, Adriel Herrero Díaz, Sandra López Berrio, César David Abreu Pereira
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
You are free of:
- Share copy and redistribute the material in any medium or format
- Adapt Remix, transform and build from material
- The licensor cannot revoke these freedoms as long as you follow the terms of the license
Under the following terms:
- Attribution - Oh, it's a good thing. You must give adequate credit , provide a link to the license, e indicate whether changes have been made . You can do it in any reasonable way, but not in such a way as to suggest that you or your use have the support of the licensor.
- Non-Commercial - Oh, it's a . You can't make use of the material with commercial purposes .
- No additional restrictions You can't apply legal terms or technological measures that legally restrict others from making any use permitted by the license.
Vancouver style
This site is licensed